Kwiiblogi zangaphambili kunye neevidiyo, sithethile kakhulu malunga neebhaktheriya zebhaktheriya okanye i-plaque biofilms, kodwa zithini kanye kanye ii-biofilms kwaye zenziwa njani?
Ngokusisiseko, iifilimi zebhayoloji bunzima obukhulu bebhaktheriya kunye nomngundo obambelela kumphezulu ngokusebenzisa into efana neglue esebenza njengeankile kwaye ibonelela ngokhuseleko kokusingqongileyo.Oku kuvumela iibhaktheriya kunye nefungi ezifakwe ngaphakathi kuyo ukuba zikhule ecaleni kwaye ngokuthe nkqo.Ezinye ii-microorganisms ezidibana nesi sakhiwo sincangathi nazo ziye zifakwe kwifilim evelisa iibhaktheriya ezininzi zebhaktiriya kunye neentlobo zefungi ezidibana zibe ngamakhulu kunye namakhulu amaleya ubukhulu.I-matrix efana neglu yenza ukunyanga ezi filimu zebhayoloji kube nzima kakhulu kuba ii-antimicrobials kunye ne-immune factor azikwazi ukungena nzulu phakathi kwezi bhanyabhanya zenza ezi zinto ziphilayo zixhathise kunyango oluninzi.
Ii-biofilms zisebenza kakhulu kangangokuba zikhuthaza ukunyamezelana namayeza okubulala iintsholongwane ngokukhusela ngokwasemzimbeni iintsholongwane.Banokwenza iibhaktheriya ukuba zikwazi ukumelana ne-1,000 ngakumbi kumayeza okubulala iintsholongwane, amayeza okubulala iintsholongwane kunye nomkhosi wokhuselo lomzimba kwaye yamkelwa zizazinzulu ezininzi njengenye yezona zizathu ziphambili zokuxhathisa amayeza okubulala iintsholongwane kwihlabathi jikelele.
Iifilimu ze-Biofilm zinokwenza kuzo zombini iindawo eziphilayo nezingaphiliyo ezibandakanya amazinyo (i-plaque kunye ne-tartar), ulusu (njengamanxeba kunye ne-seborrheic dermatitis), iindlebe (i-otitis), izixhobo zonyango (ezifana ne-catheters kunye ne-endoscopes), i-kitchen sinks kunye ne-countertops, ukutya kunye nokutya. izixhobo zokucubungula, iindawo ezibhedlele, imibhobho kunye nezihlungi kwiindawo zokunyanga amanzi kunye ne-oyile, igesi kunye nezixhobo zokulawula inkqubo yepetrochemical.
Zenziwa njani ii-biofilms?
Iintsholongwane kunye nokungunda zihlala zikhona emlonyeni kwaye zihlala zizama ukwenza ikholoni kumphezulu wamazinyo ngokubambelela ngokuqinileyo kwinto efana neglu ekhankanywe ngasentla.(Iinkwenkwezi ezibomvu neziluhlaza kulo mzekeliso zimele iibhaktheriya kunye nomngundo.)
Ezi bhaktheriya kunye nefungi zifuna umthombo wokutya ukuze zincede ekukhuleni nasekuzinzeni kwe-membrane.Oku kuqala kwi-ion yentsimbi efumaneka ngokwemvelo emlonyeni njengentsimbi, i-calcium kunye ne-magnesium, phakathi kwezinye izinto.(Amachaphaza aluhlaza kulo mzekeliso amele ezi ion zentsimbi.)
Ezinye iibhaktheriya ziyadibana kule ndawo zenze ii-micro-colonies, kwaye ziyaqhubeka nokukhupha le nto incangathi njengomaleko okhuselayo onjengedome okwaziyo ukubonelela ngokhuseleko kwi-immune system, antimicrobials kunye nezibulala-ntsholongwane.(Iinkwenkwezi ezimfusa kulo mzekeliso zimele ezinye iintlobo zebhaktiriya kwaye umaleko oluhlaza umele ukwakhiwa kwematrix yebhayoloji.)
Phantsi kwale biofilm incangathi, iibhaktheriya kunye nomngundo ziphindaphindeka ngokukhawuleza ukwenza i-3-dimensional, iqoqo elineeleya ezininzi ekwaziwa ngokuba yi-dental plaque eneneni eyi-biofilm eshinyeneyo engamakhulu kunye namakhulu amaleya ubunzulu.Nje ukuba i-biofilm ifikelele kubunzima obubalulekileyo, ikhupha ezinye iibhaktheriya ukuba ziqalise le nkqubo yekholoni kwezinye iindawo eziqinileyo zamazinyo eziqhubela phambili ukwakheka kweplaque kuyo yonke imiphezulu yamazinyo.(Umaleko oluhlaza kulo mzekeliso ubonisa i-biofilm iya isiba ngqindilili kwaye ikhula izinyo.)
Ekugqibeleni icwecwe lebhayofilm, lidityaniswe nezinye iiminerali ezisemlonyeni ziqalisa ukubala, ziziguqule zibe yinto eqine kakhulu, ejijekileyo, efana nethambo ebizwa ngokuba yicalculus, okanye itartar.(Oku kuboniswa kumzekeliso ngocweyo lwefilim etyheli isakhiwo ecaleni kwentsini emazantsi amazinyo.)
Iintsholongwane ziyaqhubeka nokwakha iileya ze-plaque kunye ne-tartar ezingena ngaphantsi kwegumline.Oku, kudityaniswe neendawo zokubala ezibukhali, ezijijekileyo ziyacaphukisa kwaye zikhuhle iintsini phantsi kwentsini enokuthi ekugqibeleni ibangele isifo se periodontitis.Ukuba iyekwa inganyangwa, inokuba negalelo kwizifo zesistim ezichaphazela intliziyo yesilwanyana sakho sasekhaya, isibindi kunye nezintso.(Umaleko wefilimu emthubi kulo mfanekiso umele icwecwe lebhayofilm lilonke libalwa kwaye likhule phantsi kwentsintsi.)
Ngokoqikelelo olwenziwa yiNational Institute of Health (NIH, USA), malunga nama-80% azo zonke izifo ezibangelwa ziibhaktheriya ezibangelwa ziibhaktheriya.
I-Kane Biotech igxile ekuphuculeni itekhnoloji kunye neemveliso eziqhekeza i-biofilms kunye nokutshabalalisa ibhaktheriya.Ukutshatyalaliswa kwe-biofilms kuvumela ukunciphisa kakhulu ukusetyenziswa kwe-antimicrobials kwaye ngoko ke kuthatha inxaxheba ekusebenziseni ngokunengqiqo kunye nokusetyenziswa okusebenzayo kwezi zixhobo zonyango.
Itekhnoloji ephuhliswe yi-Kane Biotech ye-bluestem kunye ne-silkstem inefuthe elihle kwimpilo yabantu, yezilwanyana kunye nokusingqongileyo.
Ixesha lokuposa: Jul-10-2023